PhD studentship position available
Natural product pharmacology – Novel synthesis methods for the production of human circulating metabolites of natural products
A University of Hull-funded PhD studentship is available for a project investigating novel methods of synthesising circulation metabolites of natural products. Plant-derived polyphenols are an interesting class of natural product that have been identified to have some pharmacological activities in a range of disease states including cardiovascular diseases (Molecular Nutrition and Food Research, 60, 4, 787-797). These compounds undergo significant metabolic processing in humans, however these metabolites are not available for use in in vitro drug screening approaches, due to substantial challenges using traditional synthesis methods. This project will utilise existing expertise in microfluidic synthesis technology at the University of Hull, to develop and characterise such devices for the synthesis of polyphenolic metabolites.
Applicants should have an undergraduate degree (1st class) or Masters degree in chemistry or biochemistry. Applicants should have knowledge or practical experience of microfluidic technology and its application to synthesis, and practical experience of analytical chemistry techniques (e.g. HPLC/LC-MS, NMR, etc.). This project is co-supervised by Dr Huw Jones, Prof. Nicole Pamme, and Dr Kevin Welham. Enquiries should be directed to Dr Huw Jones (huw.jones@hull.ac.uk).
Application deadline: Monday, 18 June 2018. See full advert for more details and how to apply.
Currently we do not have any funded positions available in our group. However, if you would like to join our group in the future, please check this page regularly for up to date vacancy information.
Self-funded PhD students, Research Fellows and Visitors
If you have your own funding, an externally sponsored PhD studentship, want to apply for a Research Fellowship and are interested in our research topics, please do not hesitate to contact Prof. Pamme directly.
