magnetism and microfluidics
Magnetic particles are commonly used in bioanalysis but conventional tube-based procedures are cumbersome. In our research group, we have developed continuous flow approaches for particle sorting and on-particle processing. Read more…
radio-chemistry on-chip
We are developing microfluidic approaches to the processing and synthesis of radiopharmaceuticals utilised in PET and SPECT imaging. The motivation is to enable dose-on-demand synthesis and minimise infrastructure and lab-safety requirements due to the smaller radioactive volumes processed. Read more…
tissue-on-chip
In collaboration with biomedical researchers we are currently working on precision cut tissue slices for longitudinal studies of therapy using liver, lung, gut, brain and skin wound tissue. We are carrying out COMSOL modelling to investigate oxygen transport through such tissue slices. Read more…
pathogen analysis
We study bacteria in clinical samples, food samples and environmental samples employing microfluidic techniques such as immiscible filtration assisted by surface tension (IFAST), magnetophoresis and acoustophoresis as well as paper microfluidics. Read more…
environmental analysis
We have developed portable lab-on-a-chip systems to study the safety of drinking water and, recently, have started developing paper based analytical devices to be used by volunteers to better assess, treat and prevent contamination from pollutants that can be found in the sediments in our waterways. Read more…
materials chemistry
We produce amphiphilic drug delivery vesicles through photo-polymerisation of droplets, generate hydrogen with sunlight by immobilising bacteria on-chip and study the generation and effect of reactive oxygen species. Read more…
Nicole Pamme - Research Group 